Craving an authentic Italian sub packed with layers of premium meats, savory cheese, and crisp vegetables? Skip the sandwich shop and create this irresistible Italian Sub recipe right in your own kitchen! It’s the perfect easy, hearty, and satisfying meal for a busy weeknight dinner or a delightful weekend lunch.
There’s something uniquely satisfying about Italian-inspired cuisine, and it’s always a surefire hit in our home. If you adore the vibrant flavors of Italy as much as we do, you might also enjoy this refreshing Italian Chopped Salad or these incredibly tender Slow Cooker Italian Beef Sandwiches for your next family meal.

Mastering the Art of the Homemade Italian Sub
Life can get incredibly hectic, especially when juggling family commitments and a packed schedule. We often find ourselves with limited time to whip up a delicious and nutritious dinner during the week. That’s precisely why my go-to menu is increasingly filled with fast, easy, and undeniably satisfying recipes.
This homemade Italian Sub recipe is a true lifesaver. Who doesn’t love a well-made sandwich? And it gets even better when it’s piled high with an assortment of premium Italian cold cuts, creamy cheese, and a medley of crunchy, fresh vegetables. It’s a meal that consistently earns rave reviews from my entire family, disappearing almost as quickly as it’s assembled!
Why Make Your Own Italian Sub?
While grabbing a sub from your local deli is convenient, crafting one at home offers numerous advantages. First, you gain complete control over the quality and quantity of your ingredients. You can select your favorite deli meats, choose the freshest produce, and customize the dressings to your exact taste. Second, it’s often more cost-effective, especially when feeding a crowd. Lastly, there’s an immense satisfaction in creating a deli-quality sandwich that rivals any takeout option, all from the comfort of your kitchen. It’s an ideal solution for a quick lunch, a hearty dinner, or even a picnic spread.

Essential Ingredients for Your Italian Sub
The beauty of an Italian sub lies in its simplicity and the quality of its components. Here’s a detailed look at what you’ll need and how to select the best options for a truly remarkable sandwich:
- Mayonnaise: This forms the creamy base of one of our two signature dressings. Feel free to use your preferred brand, whether it’s full-fat for richness or a low-fat variety.
- Red Wine Vinegar: A traditional choice for its sharp, tangy flavor that cuts through the richness of the meats and cheese. If you’re looking for an alternative, a good quality balsamic vinegar could offer a delicious, slightly sweeter depth.
- Italian Seasoning: This aromatic blend brings all the classic Italian herb notes. If you don’t have a pre-made blend, a combination of dried oregano and basil will work wonderfully, bringing that quintessential Mediterranean essence to your sub.
- Salt and Pepper: Crucial for seasoning both the mayonnaise mixture and the oil and vinegar dressing. Don’t underestimate how a touch of salt and freshly ground black pepper can elevate all the flavors in the sandwich. Season to your personal taste.
- Olive Oil: Extra virgin olive oil is highly recommended here, as its distinct flavor will shine through in the final dressing. Choose an olive oil you genuinely enjoy the taste of, as it contributes significantly to the sub’s overall profile.
- Parmesan Cheese: Finely grated Parmesan is key for the oil and vinegar dressing. Its salty, umami notes blend seamlessly, adding an extra layer of savory flavor. Ensure it’s very finely grated so it disperses evenly throughout the liquid.
- Sub Rolls: The foundation of your sandwich! Good quality bread is paramount. You can opt for classic sub rolls, hoagie rolls, or a crusty Italian loaf. The best choice will be one that is fresh, has a slight chew, and can hold up to all the delicious fillings without getting soggy.
- Cheese: Provolone is a widely recognized and beloved choice for Italian subs due to its mild, slightly nutty flavor and excellent melting properties. However, don’t hesitate to experiment with other cheeses like fresh mozzarella for a milder taste or even a sharp cheddar for a bolder profile.
- Meats: This is where you can truly let your creativity (and cravings) guide you! A classic Italian sub boasts a variety of deli meats, each contributing its unique texture and flavor. My preferred combination includes pepperoni (for a touch of spice), salami (savory and rich), ham (mild and salty), capicola (spicy cured pork), and mortadella (smooth and subtly spiced). Aim for approximately 1/4 to 1/3 pound of total meat per sandwich for a truly satisfying experience. Feel free to add or substitute with other Italian favorites like prosciutto or soppressata.
- Vegetables: Fresh, crisp vegetables add essential crunch, color, and tang. I keep it simple with classic shredded lettuce, juicy sliced tomatoes, thinly sliced red onions for a sharp bite, and tangy pepperoncini peppers. Banana peppers are also an excellent alternative if you prefer them. Consider adding black olives, bell peppers, or even a few thinly sliced cucumbers for additional texture and flavor.

Step-by-Step Guide to Assembling Your Perfect Italian Sub
Crafting an Italian sub is a straightforward process, but careful layering ensures every bite is bursting with flavor and texture. Follow these simple steps for a truly exceptional sandwich:
STEP 1: Prepare the Mayonnaise Mixture. In a small bowl, combine the creamy mayonnaise with 1 tablespoon of red wine vinegar and 1 teaspoon of Italian seasoning. Stir these ingredients together until well blended. Taste the mixture and season with salt and pepper as needed to achieve your desired flavor profile. Set this aside as your savory spread.
STEP 2: Create the Oil and Vinegar Dressing. In a separate bowl, whisk together the extra virgin olive oil, the remaining 2 tablespoons of red wine vinegar, the finely grated Parmesan cheese, and the remaining 1 teaspoon of Italian seasoning. Continue whisking until the ingredients are thoroughly combined. Season this dressing with salt and pepper to taste, ensuring it has a vibrant and tangy flavor. This dressing will provide that signature zesty finish.

STEP 3: Prepare the Sub Rolls and First Layers. Carefully slice your sub rolls lengthwise, ensuring you don’t cut all the way through, creating a hinge on one side. Evenly spread the prepared mayonnaise mixture on the inside of both halves of each sub roll. This layer adds moisture and a rich, savory foundation. Next, arrange slices of provolone cheese over the mayonnaise on both sides of the roll. Then, begin layering your chosen Italian deli meats, distributing them generously across the cheese. For the best stability and flavor distribution, try to layer equal amounts of meat on both sides of the sandwich.
STEP 4: Add the Fresh Vegetables. Once your meats are perfectly arranged, it’s time for the vibrant crunch of the vegetables. Place the shredded lettuce, sliced tomatoes, thinly sliced onions, and pepperoncini peppers directly on top of the layered meats. Positioning the vegetables in the middle of the sandwich helps them stay contained once the sub is folded.

STEP 5: Drizzle and Serve. To complete your masterpiece, generously drizzle the prepared olive oil and vinegar mixture over the top of the vegetables. This dressing not only adds a burst of tangy flavor but also helps to lightly moisten the fresh produce. Carefully fold the sandwich in half, bringing the two sides together. For easier handling and serving, you can cut the completed sub in half crosswise. Serve immediately and savor every delicious bite!

Pro Tips for the Best Italian Sub
Achieving a truly outstanding Italian sub goes beyond just good ingredients. Here are some expert tips to elevate your homemade creation:
- Thinly Sliced Deli Meats and Cheese: This is a game-changer! Whenever possible, ask your deli counter to slice the meats and cheese extra thin. Thin slices create a more enjoyable texture, allowing the flavors to meld beautifully without overwhelming your palate. When you layer thin slices, you get more flavor in each bite. I’ve found that having the deli handle this makes a significant difference, especially for items like ham and provolone that can be thicker if pre-packaged.
- Source Quality Ingredients: Don’t settle for subpar options. A good Italian sub thrives on high-quality ingredients. If your usual grocery store deli doesn’t offer a wide selection of Italian meats, consider visiting a specialty Italian market or a larger supermarket chain (like Kroger, as mentioned in the original recipe) that is known for a robust deli section. The flavor profile of capicola, mortadella, and other specialty meats can truly make your sub exceptional.
- Strategic Layering is Key: While assembling your sandwich, try this layering technique for optimal stability and flavor distribution: after spreading the mayonnaise, layer cheese on both sides of the roll. Then, arrange an equal amount of various meats on each side. Finally, place your vegetables on top of the meats. This way, when you fold the two halves of the sandwich together, the vegetables are nestled securely in the middle. This method helps the sandwich hold together better, preventing fillings from spilling out with every bite.
- Don’t Skimp on the Dressings: The mayonnaise mixture and the oil and vinegar dressing are crucial for moisture and flavor. Be generous but not excessive. They bring the whole sandwich together, adding that signature tang and richness.
- Customization is Encouraged: While this recipe provides a fantastic base, feel free to adapt it to your preferences. Love more heat? Add extra pepperoncini or a dash of red pepper flakes to your dressing. Prefer a different cheese? Experiment with fresh mozzarella or even a sharp provolone. The possibilities are endless!
- Serving Temperature: Italian subs are generally best served at room temperature or slightly chilled, allowing the flavors of the meats and dressings to fully develop.
- Make Ahead Tips: You can prepare the mayonnaise mixture and the oil and vinegar dressing a day in advance and store them in the refrigerator. Chop your vegetables ahead of time as well. Assemble the subs just before serving to prevent the bread from getting soggy. If you must assemble slightly ahead, wrap them tightly in parchment paper or plastic wrap and refrigerate for up to an hour.

More Delicious Sandwich Recipes to Explore
If you’re a sandwich enthusiast, you’re in for a treat! Discover more exciting recipes that transform simple ingredients into extraordinary meals:
- Spicy Cajun Cheesesteak Sandwiches
- Steak Sandwich Recipe with Worcestershire Mayonnaise
- Three Cheese and Tomato Melt
- Roast Beef Panini
- Pimiento Grilled Cheese
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Italian Sub
Filled with a delightful combination of cheese and abundant Italian meats, this homemade Italian Sub recipe is a perfect alternative to a sandwich shop, offering an easy and satisfying dinner at home.
- Author: Deborah Harroun
- Prep Time: 15 minutes
- Total Time: 15 minutes
- Yields: 4 servings
- Course: Main Course, Sandwich
- Cuisine: Italian
Ingredients
- 1/2 cup mayonnaise
- 3 tablespoons red wine vinegar, divided
- 2 teaspoons Italian seasoning, divided
- Salt and pepper, to taste
- 1/4 cup extra virgin olive oil
- 1 tablespoon finely grated Parmesan cheese
- 4 sub rolls or Italian loaf sections
- 8 oz sliced provolone cheese
- 1/4 lb deli-sliced pepperoni
- 1/4 lb deli-sliced salami
- 1/4 lb deli-sliced ham
- 1/4 lb deli-sliced capicola
- 1/4 lb deli-sliced mortadella
- 1/2 cup thinly sliced onion (red onion recommended)
- 1-2 ripe tomatoes, thinly sliced
- 3 cups shredded lettuce (iceberg for crunch)
- Banana peppers or pepperoncini, for serving
Instructions
- In a small bowl, combine the mayonnaise, 1 tablespoon of the red wine vinegar, and 1 teaspoon of the Italian seasoning. Season generously to taste with salt and pepper. Set this creamy mixture aside.
- In another separate bowl, whisk together the olive oil, the remaining 2 tablespoons of red wine vinegar, the Parmesan cheese, and the remaining 1 teaspoon of Italian seasoning. Season this vinaigrette mixture to taste with salt and pepper.
- Carefully cut each sub roll in half lengthwise, ensuring you do not cut all the way through, leaving one side hinged. Divide the prepared mayonnaise mixture evenly among the sandwiches, spreading it thoroughly on both interior halves of each roll.
- Begin layering the fillings. Place even amounts of the sliced provolone cheese on each side of the sub roll. Then, arrange the various deli meats (pepperoni, salami, ham, capicola, mortadella) over the cheese, distributing them evenly across both halves of each sandwich. For best results, consider folding the meats to create volume.
- Add the fresh vegetables: onions, tomatoes, pepperoncini (or banana peppers), and the shredded lettuce. Layer them generously over the meats.
- Drizzle the prepared olive oil and vinegar mixture generously over the lettuce and vegetables in each sandwich.
- Carefully fold the sandwiches in half, pressing gently to secure the fillings. If desired, cut each sandwich in half crosswise before serving. Enjoy your delicious homemade Italian sub immediately!
Recipe Notes:
Nutrition information provided is an estimate only. Various brands and products can alter nutritional counts. Any nutritional information should be used as a general guide and not as a substitute for professional advice.
Nutrition Information
Serving: 1 sandwich, Calories: 1199 kcal (60%), Carbohydrates: 57g (19%), Protein: 56g (112%), Fat: 84g (129%), Saturated Fat: 59g (369%), Polyunsaturated Fat: 15g, Monounsaturated Fat: 19g, Trans Fat: 0g, Cholesterol: 127mg (42%), Sodium: 2997mg (130%), Potassium: 338mg (10%), Fiber: 4g (17%), Sugar: 7g (8%)
Keywords: Italian Sub, sandwich recipe, homemade Italian sub, deli sandwich, easy dinner
